While following the entire treatment regimen and protocol to detox one’s body from narcotics or Kratom, it is important that one focuses on the additional things like supplements and exercise, to hasten the process and improve the overall detoxification rate.

Though Kratom withdrawal is not as severe as that of Opiate, nevertheless it also needs a set of supplements to be cured. The market has many supplements to improve the results of detoxification, but mostly these supplements do you less benefit.

This article focuses on the supplements that help one to get rid of the withdrawal symptoms of Kratom and Opiate. However, it is important to proceed with a proper medicated treatment and not just solely rely on these supplements.

Kratom and Opiate withdrawal supplements can be considered as an adjuvant in the treatment of Opiate and Kratom addiction.

Why is there a need for Kratom and Opiate withdrawal supplements?

Supplements help fasten the process of Opiate and Kratom withdrawal. It eases the withdrawal symptoms and reduces kratom and opiate tolerance. Supplements are safe, and they have very few side effects and are not habit forming. Supplements help you mitigate the effects of daytime withdrawal even in the acute stage of withdrawal that is from day 1-5.

Withdrawal effects of Kratom and Opiate

Most of the withdrawal effects of Kratom and Opiate are similar, but the ones associated with Opiates are more intense and long-lasting.

Some of the withdrawal symptoms are diarrhea, restlessness, irritability, high blood pressure, craving for Kratom/Opiates, sweating, abdominal cramps, and muscle pain with fits, chills and shaking, etc. The patient may also experience hostility, aggression, runny nose and joint pain. Supplements that are taken for Kratom and Opiate Withdrawal are:

  • Kava

Also called kava kava, having kavalactones is responsible for alleviating withdrawal symptoms like depression and enhances mental clarity. It also acts as an anxiolytic and helps in reducing stress levels. However, its use for a long period of time has been contraindicated in patients with liver diseases as it causes liver disorders like cirrhosis.

  • Phenibut

It is one of the best supplements to get rid of the pain that is experienced by patients during the acute withdrawal phase. Phenibut is used by patients suffering from OCD, post-traumatic stress disorder and every sort of narcotic withdrawal.

Phenibut alleviates the symptoms of withdrawal like anger, stress, anxiety, mood swings, restless leg syndrome, muscle cramps and aches as well as insomnia. The problem with Phenibut is that one develops tolerance very quickly to it, so take it infrequently and in very low doses.

  • Passion Flower

The flavonoids present in Passion flower are responsible for alleviating withdrawal symptoms like GI distress, nervousness, and excitability, insomnia, etc. The mechanism of action is that the flavonoids act as inhibitors of monoamine oxidases.

This results in raised levels of serotonin, epinephrine, and norepinephrine along with dopamine. Thus, the symptoms of depression, fatigue and stress are cured. Passion flower also increases the release of GABA that acts as an anxiolytic.

  • 5-Hydroxytryptophan

This supplement works by enhancing the levels of serotonin in the central nervous system. It helps in improving mood and cures insomnia. However, it should be used carefully with other drugs as it might cause serotonin syndrome.

  • Agmatine Sulphate

This supplement is used to avoid the development of withdrawal symptoms of Kratom. The dose is 500mg taken thrice a day.

  • Rhodiola Rosea

This herb increases the dopamine levels in the brain. Dopamine is responsible for increasing pleasure levels and making one feel happy and enjoy activities. Thus Rhodiola reduces fatigue and boosts energy levels. It is an adaptogenic supplement.

  • N-Acetyl Carnitine

It helps in alleviating the withdrawal symptoms associated with Kratom

  • Bacopa

This herbal supplement acts as an anxiolytic and helps in reducing stress levels. It works by acting on the serotonin and dopamine receptors in the brain. It also cures the GI distress associated with Kratom and Opiate withdrawal.

  • Ashwagandha

This supplement is being taken in different parts of Africa and India and it reduces stress levels and improves mood by decreasing the cortisol levels in the body. This way it also cures insomnia, anxiety, and depression. It has negligible side effects.

  • Black Cumin Seed Oil

It is responsible for reducing muscle cramps, curing headache and hypertension. It can be used to taper the dose of Kratom thus helping in quitting Kratom.

  • Ibogaine Root

It is a hallucinogenic root that recommended for withdrawal of narcotics. It is stated by some users that Ibogaine helps in easing withdrawal symptoms within 24 hours of consumption. Apparently, it acts by resetting the opiate receptors in the body, and thus the dependency for opiates is reduced.

  • Calcium and Magnesium

These two minerals are required for steady conduction of nerve impulses and taking them as supplements in the withdrawal phase can relieve anxiety as well as muscle aches and cramps. 2000mg of Calcium and 1000mg of Magnesium per day is the recommended dose.

  • B-Complex Vitamins

Vitamin B series relieve stress and tension headaches. They provide balance to nerves and reduce the agitation caused by opiate addiction. It also acts as an anxiolytic and helps in calming nerves. Make sure that the vitamin is pure and of high quality to achieve desired results.

  • Melatonin

Melatonin restores the normal sleep-wake cycle thus it can help with insomnia and other sleep disorders. However, it shouldn’t be taken frequently.

By keeping all these supplements in mind, it is necessary to know that some of these supplements may cause addiction too. So it’s important that you take these supplements in a regulated manner, modifying your diet and lifestyle at the same time to enhance the process of detoxification.

These supplements shouldn’t be taken without a proper prescription from a professional medical practitioner. The consumption of fizzy drinks and alcohol should be minimized while taking these supplements.

Also, one supplement should be taken at a time otherwise there is a risk of interaction between different drugs.

The diet should be modified in a way to ease the withdrawal symptoms. A low saturated fat plan should be followed. More carbohydrates in diet will aid the detoxification process.

Fiber should be added into diet and spices that target liver should be avoided at all costs. Most people confuse the feeling of hunger with a craving for opiates.

Therefore, it is recommended to eat regular meals and avoid fish like sardines and salmon, vegetables like broccoli and kale in the diet.

Those who go through the Kratom and Opiate withdrawal know how challenging it can get physically, mentally as well as emotionally that is why it is important to have the right tools to support you while going through this process.



  1. High dose Vitamin C should have been the first thing on this list. None of the other things work! I know from experience. I don’t know who wrote this, but they have no idea what they’re talking about.

  2. Thank you for the info ! Kratom
    Was great for 3 years, until it was another thing for me to become dependent on. I won’t speak for other people it’s there own business if it’s for them or not. Thank you for posting helpful information instead of just vendor information !

  3. Yes, kratom was a godsend at furst, but I’ve been taking it since 2006. It does not mesh well with anti depressants, AND it can be addictive physically and psycologically. And I’m 66 now, time to rest my body. This is my own experience. Many people I know have kicked opiates, heroin etc with the help of kratom, but remember it is a slippery slope. Good luck


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