Are you considering combining kratom and magic mushrooms? It’s an exciting prospect, with widely varied opinions on the safety and efficacy of such combinations. But as much as these substances can be confusing to navigate – primarily if used in combination – more and more people are turning to them for their potential health benefits.

Many people turn to the natural herb kratom to combat fatigue, persistent pain, and stress. It is rising in popularity all over the globe with other psychedelics like LSD and magic mushrooms.

Kratom consumers have developed novel approaches to optimizing their experience with and benefit from the botanical. For example, some people combine their chosen kratom strain with additional substances to create a more potent mixture.

Because of the potential for additive effects, kratom specialists advise against combining kratom goods with other drugs. However, some seasoned users have attempted to mix the two to maximize their benefits.

So what do we know about the risks associated with taking kratom and magic mushrooms together or even one after another? In this blog post, we’ll explore the available research evidence so that you can make an informed decision about whether or not it’s a good idea to combine them.

What Are Magic Mushrooms?

Psilocybin and psilocin are hallucinogenic substances found in nature, and magic mushrooms are just an authorized classification of these mushrooms. Apart from freezing climates, they may be seen flourishing everywhere. They thrive on manure and rich soil, which you’ll likely encounter in nature.

They are easily accessible, which has increased their popularity for pleasure abuse, even though their usage is still prohibited by law in most nations.

The primary psychoactive components of magic mushrooms activate neurotransmitter systems, leading to altered brain activity and a corresponding shift in our perceptual framework.

What Are Magic Mushrooms Used For?

Before scientists looked at its effects on persons with mental disorders, magic mushrooms were mainly used for entertainment. However, researchers are now investigating psilocybin’s potential benefits for treating mental diseases and promoting overall health.

Psilocybin helps treat:

  • Dependency
  • Mental Illnesses Associated with Worry and Fear
  • Negative Emotions
  • Depression
  • Symptoms of Migraines and Cluster Headaches
  • Difficulties Recovering From Stress Caused By Previous Trauma (PTSD)

Psilocybin-assisted treatment is utilized to cure intractable conditions because it facilitates epiphanies on a philosophical and theological level. It may also help one gain perspective on life and grow in self-awareness.

How Much Of The Wonder Mushrooms Should You Take?

You may adjust the number of psychedelic mushrooms you take by considering your body weight and the benefits you want to feel. However, considering it is simple to take too much accidentally, it requires precise measurement to avoid unwanted consequences.

If we use Psilocybe cubensis as an example, typical dosages might look like this:

  • Low dose: 0.5 to 1.75 grams
  • Medium dose: 1.75 to 3.5 grams
  • High dose: 3.5 to 5 grams

Psilocybin mushrooms are best experienced in small quantities at first and then increased to more significant amounts as desired. Dosages above the standard should be avoided unless the user is well-versed in the material and entirely at ease in the surrounding conditions; heroic doses are explicitly prohibited.

Any Adverse Impacts Of Taking Magic Mushrooms?

When taken in the wrong frame of mind or at too high of a dosage, magic mushrooms may cause unpleasant consequences. A horrible vacation is what most people think about when they experience this. However, remember that these symptoms may last a few hours.

Consequences that are most often experienced include:

  • Uncertainty
  • Lightheadedness
  • Chronic hypertension
  • Appetite loss
  • Morning sickness
  • Psychosis
  • Shivering

What Effects Does Kratom Have When Combined With Magic Mushrooms?

Although the results of combining kratom and psilocybin mushrooms will differ from individual to individual, they may react. Due to potential adverse effects, it’s better to consult your physician before going for any combination.

One of kratom’s primary alkaloids, mitragynine, has shown promise as an antidepressant, according to the results of scientific investigations.

However, Psilocybe cubensis, one of the most common types of magic mushrooms, also achieves its psychedelic effects through binding to monoamine neurotransmitters.

Even while further research is required, these findings show that kratom may mitigate the hallucinatory impacts of magic mushrooms. Therefore, this may be an unsuitable mixture based on the intended usage.

We’ll go through how kratom and psilocybin mushrooms work together in more depth below.

Reduced Hallucinogenic Action (Antagonistic Interaction)

When we eat magic mushrooms, our serotonin levels rise, which leads to a heightened state of happiness and other consequences. However, the alkaloid in kratom called mitragynine acts as an opponent to these sensors, disrupting the mechanism.

Due to this combination, psilocybin should have less of its usual effects, particularly its psychedelic ones.

Several consumers, however, have said that they did not encounter these side effects, and some even say that kratom improved their hallucinogenic experience.

The Association Between Kratom And Psychedelics

Psilocybin, often known as magic mushrooms, belongs to the category of hallucinogenic compounds known as psychedelics because of its ability to alter one’s state of mind, thought processes, and experience. To a greater or lesser extent, kratom and other psychedelics will react in the same ways as magic mushrooms. 

According to a reddit user, Red Reishi Mushroom, when mixed with Kratom, can provide increased euphoria. Mushroom, together with kratom in a ratio of 3:2, provides increased and prolonged effect. Hence this combination can potentially be tried to enhance these magical feelings.

What Are The Risks Of Combining Kratom With Magic Mushrooms?

Consuming kratom and psilocybin together is unlikely to have any adverse effects, although it may lessen the potency of the psychedelic high. Likewise, it’s unlikely that you’ll have any future negative effects, but if you want to be safe, you may always lower your dosage or switch to a single medication.

Unfamiliar people should probably stay away from it. Ask your physician beforehand if you are already using any medications.


When used alone, neither kratom nor psilocybe cubensis poses any health risks. If used sensibly, they can provide significant positive psychological effects. Despite the lack of data, it seems likely that their impacts would balance one another out. Kratom has antipsychotic properties and may moderate the effects of psilocybin. Although it may seem like a good idea at the time, it’s best to check with your doctor before taking either of these medications together.



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