Chemistry of The Kratom Plant


The internal mechanism of kratom plant alkaloids is highly fascinating and intriguing, due to their unique structures and consequent effects upon the human body. Both Uncaria alkaloids and epicatechin are known as secondary chemicals because they are present in small quantities within kratom. Despite their reduced quantities, their effects are still beneficial and significant enough to be highlighted. This shows that kratom is a lot more than a normal narcotic.

Research pertaining to kratom’s pharmacology, primary and secondary chemicals and alkaloid receptors is still in its early stages. Further studies and research will shed light upon numerous other hidden benefits possessed by the plant.

Uncaria alkaloids of Kratom plant

The plant has a few uncaring alkaloids, which have previously been discovered in a medicinal plant known as ‘cat’s claw’. This plant is commonly found in South America and has numerous medical benefits. The most dominant Uncaria alkaloid within kratom is mitraphylline. This alkaloid has shown activity in users that reduce blood pressure, lowers blood glucose levels and acts as a vasodilator.

Moreover, it is also effective as a muscle relaxer and calms the nerves. One research has indicated that this alkaloid enhanced the ability of tested animals to retain their memory during performances. These animals were treated with amnesic drugs, and it was discovered that their memory retention performance was significantly enhanced.

Furthermore, additional research has also shown the uncaring alkaloid to be a highly effective diuretic. Though there are some doubt and uncertainty regarding whether or not it is able to increase the activity of phagocytes, like other Uncaria alkaloids.

Despite this doubt, it has been conclusively shown by research that this ability is possessed by stereoisomer iso mitraphylline, which is present within kratom.

Epicatechin alkaloids of Kratom plant

One chemical that is present within kratom and is extremely noteworthy is ‘epicatechin’. This polyphenol, which happens to be a cis-isomer of the chemical catechin, is strongly linked to the popular EGCG. It is found in increasing amounts in green tea, dark chocolate and cranberry juice.

It has a wide variety of benefits for the user, as it lowers toxins within the human body. Moreover, it lowers the number of free radicals within the blood, which lessens risks of contracting cancer.

This shows that it is a notable anti-oxidant that presents fatty cells and triglycerides from sticking to the walls of human body cells within the urinary tract. This activity prevents a plethora of diseases and illnesses and helps in treating urinary tract infections (UTI). Prevention of UTI is linked to epicatechin impairing a bacteria’s capability to stick to the tract’s walls.

Furthermore, diabetics use epicatechin as it has a lot of beneficial properties for them. For instance, it imitates insulin within the body, thereby protecting erythrocytes in a similar method. Research has also shown that epicatechin can inhibit alpha-amylase, which prevents starch being digested into absorbable glucose. This is extremely beneficial for those who are suffering from diabetes or cannot retain insulin.

Blood sugar levels are kept low as it inhibits glucose being absorbed by the intestines. Moreover, it has also shown an ability to prevent the growth and breeding of pathogenic bacteria, such as staph and E. coli. Another noteworthy capability of epicatechin is its ability to inhibit the virus known as ‘virii’ from entering and infecting human body cells, thus is has anti-viral properties.

Rate This Article
1 Star2 Stars3 Stars4 Stars5 Stars (1 votes, average: 3.00 out of 5)